LIVERFAStâ„¢
Blood-based liver evaluation test that uses
10 biomarkers and advanced technology to determine
the condition the liver
What is LIVERFAStâ„¢?
LIVERFAStâ„¢ provides a score from 0.00 to 1.00 and its estimated grade or stage, similar to
 the histopathological scoring of the liver (based on the liver biopsy classification).
- Alpha-2-Macroglobulin
- Haptoglobin
- Apolipoprotein A1
- Total Bilirubin
- GGT
- ALT
- AST
- Fasting Glucose
- Tryglycerides
- Total Cholesterol
How it Works
Physician prescribes
LIVERFAStâ„¢
Lab analyzes
10 biomarkers from
1 blood draw
Biomarker values plus age,
height, weight, gender, are
entered into the platform
LIVERFAStâ„¢ results
are available
Physician prescribes
LIVERFAStâ„¢
Lab analyzes
10 biomarkers from
1 blood draw
Biomarker values plus age,
height, weight, gender, are
entered into the platform
LIVERFAStâ„¢ results
are available
immediately
What does LIVERFAStâ„¢ Measure?
LIVERFAStâ„¢ takes inputs from 10 biomarkers and patient anthropometrics to generate a
 score from 0.00 to 1.00 that corresponds to the histopathological staging of a liver biopsy.
Fibrosis
STAGE
INTERPRETATION
FO
No fibrosis
F1
Mild fibrosis
F2
Advanced fibrosis
F1
Significant fibrosis
F4
Severe fibrosis/cirrhosis
Activity
STAGE
INTERPRETATION
aO
No activity
a1
Mild activity
a2
Moderate activity
a1
Marked activity
a4
Severe activity
Steatosis
STAGE
INTERPRETATION
sO
No steatosis (<5%)
s1
Mild steatosis(5-33%)
s2
Moderate steatosis(34-66%)
s3
Marked steatosis (≥ 67%)
Clinical Validation
LIVERFASt, the best screening tool that also stages liver fibrosis,
steatosis & inflammatory activity
LIVERFASt predicts biopsy results, ALT and AST do not
LIVIRFASt has high clinical performance for Fibrosis & Activity
LIVIRFASt Activity Test performance
MASLD population(n=223)
0.65
LIVIRFASt Fibrosis Test performance
MASLD population(n=223)
0.75
Negative Predictive Value
0.88
0.71
The concordance for cirrhosis with Liver Biopsy (n=452)
LIVERFASt
LSM
FIB-4
67/95(71%)
51/95(54%)
45/95(47%)
Integration and Usability
LIVERFAStâ„¢ seamlessly integrates into any clinical or healthcare
setting, without disrupting clinical processes or practice
Easily Run on any Browser
Screening of all at-risk patients
