FIBRONOSTICS

Application of LIVERFASt Biomarkers to Evaluate Longitudinal Hepatic Fibrosis and Inflammation after HCV cure

Application of LIVERFASt Biomarkers to Evaluate Longitudinal Hepatic Fibrosis and Inflammation after HCV cure

Hepatitis C virus (HCV) infection is a common cause of both liver cirrhosis and hepatocellular carcinoma. Successful Direct antiviral agents (DAA) therapy is associated with >95% sustained virological response . Although the goal of HCV treatment is to achieve SVR, patients with advanced fibrosis and cirrhosis still have a high risk of developing HCC. It is important to identify patients who are at risk for liver disease complications after achieving SVR.

This study aims to :

  • To evaluate the prognostic values of LIVERFASt as a noninvasive biomarker in evaluating changes in fibrosis and inflammation post-DAA therapy
  •  To identify risks associated with HCC and liver disease progression after HCV cure post-DAA.

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